Aphrodisiac activity of ethanol extract and fractions of Fadogia cienkowskii Shweinf. Rubiaceae roots in albino rats

Fadogia cienkowskii is a shrub whose roots are used in many communities of Northern Nigeria to improve sexual performance; however, there no scientific study verify this claim. This determined the effect 70% ethanol extract F. and its fractions (ethyl acetate, n-butanol, residual ethanol) on mating behaviour (mounting, intromission ejaculation) serum testosterone concentration male albino rats. Five groups rats each containing 6 were treated with 50, 100 200 mg/kg crude extract, while Sildenafil distilled water administered control groups. Another set also 12.5 25 ethyl n-butanol fractions, respectively. The significantly increased mount, ejaculation frequencies. copulation efficiency – indicative plant’s aphrodisiac potential. Significant increase was observed, which further credence It thus concluded that root have activity being more active. Key words: activity,